Obesity problem?
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March 28, 2017 - 7:58 am
As a sugar addict and obese person, I thought this was interesting. I think it would apply across the board for antipsychotics:
Dopamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy. pamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy.
Dopamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy. pamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy.
As a sugar addict and obese person, I thought this was interesting. I think it would apply across the board for antipsychotics:
Dopamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy. pamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy.
Dopamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy. pamine is a major metabolic controller. In animals dopamine along with melatonin is largely responsible for seasonal adaptation, i.e. hibernation. Human obesity is largely a hibernation response gone unchecked and chronically triggered by very high carbohyrate and abnormally decreased bright sun exposure combined with abnormal stressors (sleep deprivation and abnormal light exposure patterns - too much during sleep, not enough during wake).
In people taking zyprexa, blocking their dopamine receptors (and serotonin, and others) is making genes active that promote hibernation - they stop burning fat, stop storing fat, blood sugar increases, fertility shuts down, etc. It is no different than a hibernating animal.
In obese and diabetic humans it has been shown there is a paucity of dopaminergic signalling, and this is reversible upon glucose restriction. Downregulation of dopamine signalling is necessary to allow metabolic disorders to occur, why ? Because it is fundamentally a normal evolutionarily concerned hibernation tendency, it is only a
disease in our modern society where tehse genes are being abnormally activated, chronically, year round.
Bromocriptine helps diabetes and obesity for this reason.
Regarding the observation that people on olanzapine are not using carbohydrate for energy, I would assume that is just the natural result of blocking multiple serotonin and dopamine receptors in the body - an inability, a debilitation, in using glucose for energy. This is a natural and evolutionarily conserved result of deficient neurotransmitter signaling, which again to the body signifies seasonal change and impending winter thus a hibernation-like response (metabolic conservation involving fat accrual, sleeping more, hunger, and shut down fertility).
It's been known for awhile that when the body switches to using fat for energy this will result in hyperglycemia and thus compensatory hyperinsulinemia, which leads to body fat gain. When the body insists on burning fat even in the presence of carbohydrate, it could mean any number of things... 1) pathological insulin resistance due to damaged /deficient mitochondria (glucose cannot get into the cells because the mitochondria are deficient, mitochondria therefore burn fat primariliy and glucose in the blood is elevated)... 2) someone is taking a drug that induces hibernation and transient metabolic conservation (with deficient dopamine and serotonin, the body refuses to accept glucose, uses fat instead as in hibernation, body fat and blood sugar increase as it might in early fall to prepare for winter. Fertility decreases in response to decreased dopamine and serotonin as well, and infertility is a major feature of winter adaptation/hibernation in animals as it is in humans on dopamine receptor blockers.)
Eating less carbohydrate, particularly sugar, is the obvious intervention to control obesity. Even though increased fat utilization occurs during metabolic disorder, it is ultimately the glucose portion of the diet that triggers the fat storage and diabetes... or at least the WORST of it. If the body wants to use fat, then feed it fat. If you try to feed it sugar, all that will happen is your pancreas will spew out insulin and your liver will convert it to fat which is efficiently stored in adipose. If you avoid eating glucose food, the worst of this hyperglycemic/hyperinsulinemic tendency is controlled.
Regarding getting the "truth" out there...It's well known receptor blockers for psych illness make you a hibernating animal that sleeps 14 hours a day and has no motivation nand weighs 300 pounds. This is not breaking news. Perhaps it would eliminate the stigma against fat schizophrenics, but that's more about social status than science anyway... the poor, uneducated, mentally ill, overweight people, how unfortunate. NO one cares.
Maybe one day, in a land far away, we will treat schizophrenia and manic depression as biological illnesses and figure out what is causing them, and ultimately resolve them... rather than just shut the brain down with receptor blockers like a chemical lobotomy.
March 28, 2017 - 9:06 am
Total Posts: 110
Joined: 08-02-2011
Joined: 08-02-2011
Good information, and I can relate to the frustrations you mentioned. When I first went on Abilify a few years back, I had insatiable cravings for carbs and always felt hungry. This led me to gaining 30 pounds. I tried to eat differently, but it was like I didn't feel like I had even eaten if I didn't include hefty servings of empty carbs. I lost the weight slowly over a 6 month period after going off it back in 2014.
It is possible to lose weight on these drugs, but I think it is so much more of a fight due to the issues you mentioned. They really do make you feel like hibernation is in progress. :/ I am thankfully at a healthy BMI 2 years later, but I have gained several pounds back over the past two months from a brief time on seroquel, then a hospital stay with no exercise for 8 days, then Latuda currently. I do think though that me avoiding carbs and sugar has helped me keep from gaining too much.
The issue with Latuda for me is not that it is actually making me gain weight. It is more that I have to be sure to eat 350 calories with it, but instead of taking it with dinner and falling asleep at 7:30, I have been taking it around 9:30 with a hefty snack just to get a couple extra wake hours in the evening. Bug the trade off is I am gaining weight from eating so much so late. I see my pdoc Friday so hopefully something can be adjusted.
AAAARRGGGHHHH.....I long for the day when there will be other treatment options. I saw a documentary aboug bipolaron youtube where researchers are trying to formulate an electrical brain chip to treat bipolar the way they did for Parkinson's. Very interesting!
It is possible to lose weight on these drugs, but I think it is so much more of a fight due to the issues you mentioned. They really do make you feel like hibernation is in progress. :/ I am thankfully at a healthy BMI 2 years later, but I have gained several pounds back over the past two months from a brief time on seroquel, then a hospital stay with no exercise for 8 days, then Latuda currently. I do think though that me avoiding carbs and sugar has helped me keep from gaining too much.
The issue with Latuda for me is not that it is actually making me gain weight. It is more that I have to be sure to eat 350 calories with it, but instead of taking it with dinner and falling asleep at 7:30, I have been taking it around 9:30 with a hefty snack just to get a couple extra wake hours in the evening. Bug the trade off is I am gaining weight from eating so much so late. I see my pdoc Friday so hopefully something can be adjusted.
AAAARRGGGHHHH.....I long for the day when there will be other treatment options. I saw a documentary aboug bipolaron youtube where researchers are trying to formulate an electrical brain chip to treat bipolar the way they did for Parkinson's. Very interesting!
Current medications as of 03-28-2017
| 03-09-2017 - Present: | Buspar, 15 mg. 2x daily |
| 03-09-2017 - Present: | Lamictal, 50 mg. 25 mg AM/25 mg PM |
| 03-09-2017 - Present: | Latuda, 80 mg. 1x PM |
Good information, and I can relate to the frustrations you mentioned. When I first went on Abilify a few years back, I had insatiable cravings for carbs and always felt hungry. This led me to gaining 30 pounds. I tried to eat differently, but it was like I didn't feel like I had even eaten if I didn't include hefty servings of empty carbs. I lost the weight slowly over a 6 month period after going off it back in 2014.
It is possible to lose weight on these drugs, but I think it is so much more of a fight due to the issues you mentioned. They really do make you feel like hibernation is in progress. :/ I am thankfully at a healthy BMI 2 years later, but I have gained several pounds back over the past two months from a brief time on seroquel, then a hospital stay with no exercise for 8 days, then Latuda currently. I do think though that me avoiding carbs and sugar has helped me keep from gaining too much.
The issue with Latuda for me is not that it is actually making me gain weight. It is more that I have to be sure to eat 350 calories with it, but instead of taking it with dinner and falling asleep at 7:30, I have been taking it around 9:30 with a hefty snack just to get a couple extra wake hours in the evening. Bug the trade off is I am gaining weight from eating so much so late. I see my pdoc Friday so hopefully something can be adjusted.
AAAARRGGGHHHH.....I long for the day when there will be other treatment options. I saw a documentary aboug bipolaron youtube where researchers are trying to formulate an electrical brain chip to treat bipolar the way they did for Parkinson's. Very interesting!
It is possible to lose weight on these drugs, but I think it is so much more of a fight due to the issues you mentioned. They really do make you feel like hibernation is in progress. :/ I am thankfully at a healthy BMI 2 years later, but I have gained several pounds back over the past two months from a brief time on seroquel, then a hospital stay with no exercise for 8 days, then Latuda currently. I do think though that me avoiding carbs and sugar has helped me keep from gaining too much.
The issue with Latuda for me is not that it is actually making me gain weight. It is more that I have to be sure to eat 350 calories with it, but instead of taking it with dinner and falling asleep at 7:30, I have been taking it around 9:30 with a hefty snack just to get a couple extra wake hours in the evening. Bug the trade off is I am gaining weight from eating so much so late. I see my pdoc Friday so hopefully something can be adjusted.
AAAARRGGGHHHH.....I long for the day when there will be other treatment options. I saw a documentary aboug bipolaron youtube where researchers are trying to formulate an electrical brain chip to treat bipolar the way they did for Parkinson's. Very interesting!
Current medications as of 03-28-2017
| 03-09-2017 - Present: | Buspar, 15 mg. 2x daily |
| 03-09-2017 - Present: | Lamictal, 50 mg. 25 mg AM/25 mg PM |
| 03-09-2017 - Present: | Latuda, 80 mg. 1x PM |
April 3, 2017 - 10:33 am
Total Posts: 658
Joined: 10-21-2012
Joined: 10-21-2012
Artista what good info, I never really thought of it that way. Maybe I can make some changes that would help. If nothing else. I can go out and get some more sun. I need Vitamin D anyway.
Cat a good back I ate with my Latuda was apples with peanut butter or cheddar cheese. Good stuff and you get a serving of fruit in!
Cat a good back I ate with my Latuda was apples with peanut butter or cheddar cheese. Good stuff and you get a serving of fruit in!
Artista what good info, I never really thought of it that way. Maybe I can make some changes that would help. If nothing else. I can go out and get some more sun. I need Vitamin D anyway.
Cat a good back I ate with my Latuda was apples with peanut butter or cheddar cheese. Good stuff and you get a serving of fruit in!
Cat a good back I ate with my Latuda was apples with peanut butter or cheddar cheese. Good stuff and you get a serving of fruit in!
Joined: 06-12-2011